Profile options greyed out
In this example, the profile is Active and in "Editing" mode and it isn't possible to click any profile options on the right.
The options 'Active' and 'Edit' are disabled because this profile is already set as active and you are currently editing it; in contrast, the other profiles allow you to select 'Active' and 'Edit'; the 'Duplicate' option is also disabled because you have reached the maximum number of profiles.
If you delete a different profile, you will then be able to duplicate a profile - note that the 'Delete' option is disabled for 'The Kitchen Sink View FR' because you cannot delete a profile that is currently active.